Pathogen control in- and around the animal
In the intensive livestock industry, pathogens in the gastrointestinal tract lead to decreased reproduction and growth performance, high mortality rates and lower profitability. Above that, pathogens in the animal habitat need to be considered as well.
When making a distinction between pathogens, ranging from bacteria to fat-enveloped viruses, it becomes evident that it is difficult to find a universal solution for pathogenic challenges.
FRAmelco offers an application that controls both Gram+ and Gram- bacteria as well as a solution for Fat-enveloped viruses.
At FRAmelco, glycerides are used to target specific pathogens as certain glycerides have a surprisingly selective effect on the inhibition of pathogens.
such as: E. coli and Salmonella
Gram- bacteria typically have more complex inner and outer membrane structures, making disruption of the cell membrane more difficult.
Still, glycerides can enter the bacteria like organic acids and alternate the DNA structure of the bacteria from the inside. After that, the cell loses its ability to produce invading proteins and will not survive.
such as: Clostridium Perfringens and Enterococcus
Gram+ bacteria typically have a simple membrane structure. Glycerides and the molecules that construct the bacterial membranes look very much alike. Therefore, they can easily interfere with each other.
This means that glycerides can disrupt the bacterial membrane after which it loses its structure.
Bacteria are not able to develop resistance against glycerides, which gives us the cutting edge in making it a successful tool to reduce curative antibiotic usage.
such as: Newcastle disease (ND), Infectious Bronchitis (IB), African Swine Fever (ASF) and PRRS.
Besides their strong antimicrobial effects, glycerides possess strong antiviral properties and are effective against fat-enveloped viruses. Their mode of action disrupts the fat envelope after which the virus completely disintegrates.
Evidence suggests that fat-enveloped viruses are, just like their microbial pathogenic companions, unable to develop resistance against glycerides.
Stronger effect on pathogen control
Organic acids are widely used to reduce pathogenic pressure, but research has shown that glycerides of fatty acids have a much stronger antimicrobial effect. Above that, under certain viral challenges these glycerides have shown to be 8 times more effective than their fatty acid counterparts. Demonstrating the stronger properties on pathogen control.
Reduce antibiotic usage with FRA Pathogen Control
Restrictions on therapeutic usage of antibiotics have led to increasing demands for antibiotic-free solutions. FRAmelco offers feed additives designed to control pathogenic pressure.
In the absence of Antibiotic Growth Promoters (AGPs), pathogen control applications were tested in practice. Results indicate significant higher final body weight and a significant lower FCR. Providing great economic advantages and assuring the health and safety of farmers and consumers.
- Final Body Weight
- Antibiotic usage
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